What is Paraprotein and What Des it Mean for the Myeloma Patient?

http://www.freelite.co.uk/animationfast-60.asp



Above is a link to an animated explanation of the effects on the kidney of the paraprotein which is created by malignant monoclonal plasma cells in Multiple Myeloma. If you may have been curious as I was where the paraproteins go when they don't show up in the free light chain urine tests, this will answer some questions for you. It also explains the kappa : lamda ratio and other topics related to free light chain analysis. This web site has a lot of good information. Of course, you have to keep in mind these folks sell a freelite test which they are advocating with this infomercial.



This might be one of the few places you can go to get a complete description of this subject. My type of MM is lamda secretory. However, the free light chains have never showed up in my freelite tests which, as explained by this animation, is a relatively good thing. I have asked doctors where the paraprotein goes if it is being secreted but does not show up in the urine. So far, I have never gotten as complete an explanation as the one presented here. So, maybe you have been curious too. If so, here is what appears to be a very good explanation.